In a statement today, Malaysia Airlines said the Kuala Lumpur to Dubai flight frequency will therefore increase from one to four times daily.
All flights will be operated on Emirates aircraft.
"The new codeshare will give customers convenient connections to Emirates more than 90 global destinations.
"This includes 38 destinations in Europe on a daily and even double daily basis for key European cities such as Paris, Rome, Munich, Frankfurt, Madrid, and Barcelona, as well as Canada and Latin America," it said.
The partnership will also see the Malaysia Airlines and Emirates frequent flyer programmes aligned, giving customers expanded opportunities to earn and redeem points.
Chief Executive Officer Christoph Mueller said the partnership allows guests to travel seamlessly to major cities around the world, whilst enjoying increased rewards through the loyalty programmes.
"We will be able to offer Kuala Lumpur as a hub to connect to South East Asia and Dubai for connections to Europe, Middle East and North and South Africa," he added.
The details of the benefits will be shared progressively over the next quarter. The service to Dubai will be operated thrice daily on a Boeing 777 and once, on the Airbus 380.
Malaysia Airlines will also suspend its Kuala Lumpur-Dubai route by Feb 15 and re-accommodate passengers on the codeshare flights with Emirates.