India has most COVID-19 cases in two months, worst-hit Kerala in focus

Densely populated Kerala, on India's southern tip, accounted for nearly 70% of the 47,092 new infections and a third of deaths, a week after it celebrated its biggest festival during which family and social gatherings were common.

"With cases rising in Kerala, adequate steps should be taken to contain the inter-state spread of COVID-19," Health Minister Mansukh Mandaviya said in a statement after speaking with his state counterparts in Tamil Nadu and Karnataka, which border Kerala.

He asked them to increase vaccination in the districts close to Kerala. India has so far administered 662 million doses, with at least one dose in 54% of its 944 million adults and the required two doses in 16%.

Vaccinations have soared in recent days as supplies have improved. And as more than two-thirds of Indians already have COVID-fighting antibodies, mainly through natural infection, experts think another national surge in cases will be less deadly than the last one in April and May when tens of thousands of people died and hospitals ran out of beds and oxygen.

Also offering hope is a recent non-peer-reviewed study done in Kerala that showed that one dose of the AstraZeneca shot, the mainstay of India's immunisation drive, generates 30 times more antibodies in previously infected people than fully inoculated ones who never contracted the virus.

"A decently managed vaccination programme, along with the hybrid immunity we're seeing now, makes a massive third wave unlikely," said clinical immunologist and rheumatologist Padmanabha Shenoy, who led the study and was referring to the immunity from natural infection and one vaccine dose.

The federal government, nevertheless, has warned that like in Kerala, the rest of India could also see a rise in infections around the festival season starting this month and ending in early November.

Some parents are also worried about the reopening of physical classes - voluntary and mainly for middle school and above - in the capital Delhi and states like Gujarat.