Thai protesters besiege PM's crisis HQ

The spike in violence has punctured hopes of an easing of a three-month political standoff in which 16 people have been killed -- both demonstrators and policemen -- and hundreds injured in gunfire and grenade blasts.

The backdrop to the unrest is a nearly decade-long political rift between opponents and supporters of Yingluck's brother, fugitive former premier Thaksin Shinawatra, that has unleashed a series of rival street protests.

Several thousand anti-government protesters massed outside the office of the permanent secretary of defence in a Bangkok suburb where Yingluck has held meetings over the last few weeks, after being driven out of her besieged headquarters in the government district.

The premier was not believed to be inside at the time. Tensions eased after military officials at the site agreed to talk to protest leader Suthep Thaugsuban.

"If Yingluck still comes to work here we will come every day," Suthep said.

The firebrand senior opposition figure even suggested the premier might be driven out of the country.

"We will hound her all day long until she cannot live here," he later told a cheering crowd.

"Retaliation against Yingluck must intensify."

On Tuesday violent clashes broke out after riot police tried to clear rally sites in the capital's historic district.

Chaotic scenes ensued as explosions and gunfire shook an area of the city near the Golden Mount temple and other tourist attractions.

A policeman was shot dead and four civilians were killed, the Erawan emergency centre said in a new toll on Wednesday, while more than 60 were injured.

Police said 24 officers were among those hurt.

National Security Council chief Paradorn Pattanatabut said there was no plan to launch a new operation on Wednesday to clear protest areas, but he denied Tuesday's operation marked a defeat for the authorities.

"The operation was not a failure. At least we regained the energy ministry and 80 percent of the government complex," he said, referring to a group of state offices in the north of the capital.

The protesters are demanding Yingluck quit to allow an unelected prime minister to take office to introduce vaguely-defined reforms such as an end to corruption and alleged misuse of public funds to buy political influence.

In a new twist, the National Anti-Corruption Commission said Tuesday that it was pressing charges against Yingluck for neglect of duty in connection with a controversial rice subsidy scheme. If found guilty she could be removed from office.

More than seven years after royalist generals ousted Yingluck's brother Thaksin in a bloodless coup, the kingdom appears more politically divided than ever.

The billionaire tycoon-turned-politician fled overseas in 2008 to avoid jail for a corruption conviction, but his critics accuse him of pulling the strings of power from self-exile.

The opposition protesters, mainly from Bangkok and southern Thailand, have vowed to rid the country of the "Thaksin regime", but Yingluck insists the dispute should be resolved at the ballot box.

Pro-Thaksin parties have won every election for more than a decade, and Yingluck is counting on her family's traditionally strong support in the northern half of the kingdom to return her to power after a general election was held on February 2.

The opposition boycotted the polls and the results are not expected to be known until election re-runs are held in constituencies where voting was obstructed by protesters.