Manny Pacquiao, his promoter and his trainer all threw down the gauntlet to Floyd Mayweather after the Filipino boxer comprehensively battered the latest challenger to his world welterweight crown into defeat Sunday.

"It's been a long time since I've been wanting this fight, it has to happen," said the eight-weight world champion at the Venetian Macau after knocking down Chris Algieri six times on his way to a huge points victory.

"The fans deserve it. It's a good thing that we talk about that fight. It's time to say yes," added the World Boxing Organization welterweight champion.

His promoter Bob Arum and trainer Freddie Roach were even more direct in calling out unbeaten light middleweight champion "Money" Mayweather, who competes with Pacquiao for the moniker "best pound-for-pound boxer in the world".

Mayweather and his promoters have previously found reasons to avoid the fight, but the 82-year-old Arum, who has been trying to secure the match for almost four years, said "enough is enough".

"No excuses. Manny knocked Algieri down six times in one fight. That's twice as many knockdowns as Mayweather has had in all his fights in the last 12 years," he taunted.

"All they have to do to is pick up the telephone. I'll be at the phone. Manny will be at his phone," added Arum.

Mayweather potentially has more to lose in a fight against Pacquiao. He has a perfect 47-0 record and has won world titles at five different weights, but a defeat at the Filipino congressman's hands could blot that streak.

Pacquiao's trainer Freddie Roach claimed there would always be a question mark over the pair's careers if they never met in the ring.

"I think there will ... always be an asterisk on their records," said Roach.

"Let's face it, the best should fight the best and they've been the best guys out there.

"This is something that will haunt them forever if it doesn't happen."

Roach said as much he wanted Mayweather to come to the table, he also knew that it would be the toughest assignment of his glittering Hall of Fame training career to prepare Pacquiao for it.

"He will be the best opponent that we've ever faced. I will really have to do my homework with Mayweather because he puts a lot of things together a lot better than most fighters."

However Roach was more confident that it would happen after Pacquiao's latest demolition job on the WBO light welterweight champion Algieri.

"Put it this way, I'm starting to watch tapes of Mayweather," he revealed.

Pacquiao mocks Mayweather in a new TV commercial for Footlocker which he mimicked in the post-fight press conference. "He's going to fight me?! Yes! Yes!" squealed Pacquiao to huge laughter all round.