The wheel from United Flight 1001, a Boeing 757-200, was recovered in Los Angeles. "We are investigating what caused this event," United said.
The aircraft involved in Monday's incident was a nearly 30-year-old 757, according to FlightRadar24 data. Boeing ended production of the 757 in 2004.
In March, a United Boeing 777-200 jet headed for Japan lost a tire mid-air following takeoff from San Francisco and landed safely at Los Angeles International Airport.