Police described what they called "tumultuous and violent conduct" by protesters on the city's Southeast Stark Street.
"Fire bombs were thrown at officers, injuring at least one community member", police said https://bit.ly/34lgHyK on Twitter while re-tweeting a video posted by a New York Times reporter showing fire bombs being thrown and a protester running with his legs on fire.
Portland has seen nightly protests for over three months that have at times turned into violent clashes between demonstrators and officers, as well as between right- and left-wing groups.
Police said they made arrests but did not give a number.
"There were hundreds at the beginning (of Saturday night's demonstrations). Arrests have been made, yes", police told Reuters in an emailed statement when asked about the crowd size and whether arrests were made.
Elsewhere on Saturday, armed police supporters and anti-racism demonstrators clashed in Louisville before the Kentucky Derby horse race, while Rochester police used tear gas to disperse protesters.
Demonstrations erupted around the United States following the death in May of George Floyd, a Black man, after a Minneapolis police officer knelt on his neck for nearly nine minutes.