At least 22 people were killed and dozens more wounded late Saturday in an attack possibly carried out by a suicide bomber on a wedding party in the Turkish city of Gaziantep near the Syrian border, officials said.

The explosion is the latest attack to have rocked the key NATO member in a horrific year that has seen a string of strikes blamed on Kurdish and Islamist militants as well as a bloody July 15 botched coup.

The office of Gaziantep governor Ali Yerlikaya said in a statement that 22 people had been killed and 94 wounded in "a bomb attack on a wedding".

"We condemn the traitors who organised and carried out this attack," it said.

Yerlikaya had earlier said the the explosion in the centre of the southeastern city was due to a "abhorrent terror attack", state-run news agency Anadolu reported.

Mehmet Erdogan, a ruling Justice and Development Party (AKP) lawmaker for Gaziantep said it was not clear who was responsible for the explosion but there was a "high possibility" it was a suicide attack.

The lawmaker added that it was the type of attack that could have been launched by the Islamic State (IS) group or the Kurdistan Workers' Party (PKK).

'Daish the culprit'

The explosion took place in the Sahinbey district of the city which is said to have a large number of Kurdish residents, fuelling speculation of jihadist involvement. Reports said the wedding had a strong Kurdish presence.

"Initial information suggests it is Daesh (IS) who did this," says Gaziantep MP for the AKP, Samil Tayyar, Dogan news agency said.

He added: "It is an area where many of our Kurdish brothers live."

The pro-Kurdish Peoples' Democratic Party (HDP) said its members had been present at the wedding which was also attended by many women and children.

"The aim of terror is to scare the people but we will not allow this," said Deputy Prime Minister Mehmet Simsek, who also represents Gaziantep in the Turkish parliament.

"It is barbaric to attack a wedding," he told Turkish television, adding that a suicide bombing was the likely cause.

A major city lying just 60 kilometres (37 miles) north of the Syrian border, Gaziantep has become a major hub for Syrians fleeing the civil war in their country.

But as well as refugees and opposition activists, there have long been fears it was home to a significant jihadist presence.

Turkey has already been hit by a bloody year of militant attacks in its two biggest cities that have left dozens dead.

Kurdish militants have twice struck in Ankara in deadly attacks, while IS suicide bombers have twice killed tourists in the centre of Istanbul.

Meanwhile the country is still reeling from a failed July 15 coup blamed on the US-based Islamic preacher Fethullah Gulen that has been followed by a relentless purge of his supporters from all state institutions.

Twelve people were killed on Thursday in a spate of bombings against Turkish security forces blamed on the PKK who appear to have ramped up their campaign of attacks in the aftermath of the failed coup.

As has been the case in previous attacks, Turkey's broadcasting regulator RTUK banned broadcast of footage from the scene of the attack in Gaziantep.

'More active Turkey'

The blast in Gaziantep came on the day Turkish Prime Minister Binali Yildirim vowed Ankara would play a "more active" role in the next six months in efforts to solve the over five-year Syrian civil war.

In a sign that Turkey's position was becoming gradually more aligned with Russia and Iran, he added that Syrian President Bashar al-Assad could remain temporarily during a transition period.

Iran and Russia are the main allies of Assad whereas Turkey has always insisted his exit was a precondition for the end of the conflict.

Turkey was long accused of turning a blind eye to or even abetting the rise of IS in Syria, claims it vehemently denies.

However Western states say Ankara has begun to move strongly against the group and seal its borders to jihadist traffic after the attacks blamed on IS on its soil this year.